
The RNase J-Based mostly RNA Degradosome Is Compartmentalized within the Gastric Pathogen Helicobacter pylori
Posttranscriptional regulation is a serious degree of gene expression management in any cell. In micro organism, multiprotein machines known as RNA degradosomes are central for RNA processing and degradation, and a few had been reported to be compartmentalized inside these organelleless cells. The minimal RNA degradosome of the essential gastric pathogen Helicobacter pylori consists of the important ribonuclease RNase J and RhpA, its sole DEAD field RNA helicase, and performs a serious position within the regulation of mRNA decay and adaptation to gastric colonization.
Right here, the subcellular localization of the H. pylori RNA degradosome was investigated utilizing mobile fractionation and each confocal and superresolution microscopy.
We established that RNase J and RhpA are peripheral internal membrane proteins and that this affiliation was mediated neither by ribosomes nor by RNA nor by the RNase Y membrane protein. In dwell H. pylori cells, we noticed that fluorescent RNase J and RhpA protein fusions assemble into nonpolar foci. We recognized components that regulate the formation of those foci with out affecting the degradosome membrane affiliation.
Flotillin, a bacterial membrane scaffolding protein, and free RNA promote focus formation in H. pylori Lastly, RNase J-GFP (RNase J-green fluorescent protein) molecules and foci in cells had been quantified by three-dimensional (3D) single-molecule fluorescence localization microscopy.
The quantity and dimension of the RNase J foci had been discovered to be scaled with progress section and cell quantity as beforehand reported for eukaryotic ribonucleoprotein granules. In conclusion, we suggest that membrane compartmentalization and the regulated clustering of RNase J-based degradosome hubs symbolize essential ranges of management of their exercise and specificity.
IMPORTANCE Helicobacter pylori is a bacterial pathogen that chronically colonizes the abdomen of half of the human inhabitants worldwide. An infection by H. pylori can result in the event of gastric pathologies akin to ulcers and adenocarcinoma, which causes as much as 800,000 deaths on this planet every year.
Persistent colonization by H. pylori depends on regulation of the expression of adaptation-related genes. One main degree of such management is posttranscriptional regulation, which, in H. pylori, largely depends on a multiprotein molecular machine, an RNA degradosome, that we beforehand found. On this research, we established that the 2 protein companions of this machine are related to the membrane of H. pylori Utilizing cutting-edge microscopy, we confirmed that these complexes assemble into hubs whose formation is regulated by free RNA and scaled with bacterial dimension and progress section. Organelleless mobile compartmentalization of molecular machines into hubs emerges as an essential regulatory degree in micro organism.

PEG3 Antibody |
|||
ABF9152 | Lifescience Market | 100 ug | EUR 525.6 |
PEG3 Antibody |
|||
AF9152 | Affbiotech | 200ul | EUR 420 |
PEG3 Antibody |
|||
DF13596 | Affbiotech | 100ul | EUR 420 |
PEG3 Antibody |
|||
1-CSB-PA030033 | Cusabio |
|
|
Description: A polyclonal antibody against PEG3. Recognizes PEG3 from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000 |
PEG3 Antibody |
|||
CSB-PA022042-100ul | Cusabio | 100ul | EUR 379.2 |
Description: A polyclonal antibody against PEG3. Recognizes PEG3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
PEG3 Antibody |
|||
CSB-PA022042- | Cusabio | each | EUR 402 |
Description: A polyclonal antibody against PEG3. Recognizes PEG3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000 |
Anti-PEG3 Antibody |
|||
A02541 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal PEG3 Antibody. Validated in WB and tested in Human. |
PEG3 Polyclonal Antibody |
|||
ABP55568-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of PEG3 from Human. This PEG3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PEG3 at AA range: 1010-1090 |
PEG3 Polyclonal Antibody |
|||
ABP55568-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of PEG3 from Human. This PEG3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PEG3 at AA range: 1010-1090 |
PEG3 Polyclonal Antibody |
|||
ABP55568-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of PEG3 from Human. This PEG3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human PEG3 at AA range: 1010-1090 |
PEG3 Conjugated Antibody |
|||
C34056 | SAB | 100ul | EUR 476.4 |
PEG3 Polyclonal Antibody |
|||
ES6567-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against PEG3 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
PEG3 Polyclonal Antibody |
|||
ES6567-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against PEG3 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Anti-PEG3 antibody |
|||
STJ114545 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. |
Anti-PEG3 antibody |
|||
STJ95024 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to PEG3. |
PEG3 siRNA |
|||
20-abx928229 | Abbexa |
|
|
PEG3 siRNA |
|||
20-abx928230 | Abbexa |
|
|
NH2-PEG3 |
|||
HY-W007545 | MedChemExpress | 100mg | EUR 129.6 |
PEG3 Rabbit pAb |
|||
A12671-100ul | Abclonal | 100 ul | EUR 369.6 |
PEG3 Rabbit pAb |
|||
A12671-200ul | Abclonal | 200 ul | EUR 550.8 |
PEG3 Rabbit pAb |
|||
A12671-20ul | Abclonal | 20 ul | EUR 219.6 |
PEG3 Rabbit pAb |
|||
A12671-50ul | Abclonal | 50 ul | EUR 267.6 |
OH-PEG3-Tos |
|||
20-abx085425 | Abbexa |
|
|
Tos-PEG3-Tos |
|||
20-abx085426 | Abbexa |
|
|
COOH-PEG3-COOH |
|||
20-abx085430 | Abbexa |
|
|
propargyl-PEG3-Acid |
|||
20-abx180861 | Abbexa |
|
|
N3-PEG3-NH2 |
|||
20-abx186135 | Abbexa |
|
|
N3-PEG3-OH |
|||
20-abx186195 | Abbexa |
|
|
Alkyne-PEG3-Alkyne |
|||
20-abx186246 | Abbexa |
|
|
OH-PEG3-CH2CH2COOtBu |
|||
20-abx186258 | Abbexa |
|
|
Biotin-PEG3-Azide |
|||
abx186382-1g | Abbexa | 1 g | EUR 944.4 |
Methyl-PEG3-MS |
|||
abx186609-250mg | Abbexa | 250 mg | EUR 526.8 |
NH2-PEG3-NH2 |
|||
20-abx186613 | Abbexa |
|
|
NH2-PEG3-COOH |
|||
20-abx186616 | Abbexa |
|
|
Bromo-PEG3-azide |
|||
20-abx186630 | Abbexa |
|
|
PEG3 Blocking Peptide |
|||
AF9152-BP | Affbiotech | 1mg | EUR 234 |
NHS-PEG3-NHS |
|||
ADC-L-121 | Creative Biolabs | unit | Ask for price |
N3-PEG3-CH2COOH |
|||
HY-42637 | MedChemExpress | 100mg | EUR 183.6 |
Boc-NH-PEG3 |
|||
HY-W017772 | MedChemExpress | 100mg | EUR 170.4 |
Amine-PEG3-Biotin |
|||
HY-111377 | MedChemExpress | 10mg | EUR 253.2 |
VH032-PEG3-acetylene |
|||
HY-128767 | MedChemExpress | 5mg | EUR 135.6 |
Azido-PEG3-FLAG |
|||
H-7924.0500 | Bachem | 0.5mg | EUR 459.6 |
Description: Sum Formula: C50H75N13O24 |
Azido-PEG3-FLAG |
|||
H-7924.1000 | Bachem | 1.0mg | EUR 741.6 |
Description: Sum Formula: C50H75N13O24 |
Biotin-PEG3-Acid |
|||
27421 | BPS Bioscience | 100 mg | EUR 185 |
Description: Biotinylation reagent with 3 PEG spacer. Has a carboxyl group with a free -OH that can react with activated surfaces or can be converted to another reactive functionality. |
Biotin-PEG3-Acid |
|||
27422 | BPS Bioscience | 250 mg | EUR 260 |
Description: Biotinylation reagent with 3 PEG spacer. Has a carboxyl group with a free -OH that can react with activated surfaces or can be converted to another reactive functionality. |
Biotin-PEG3-Acid |
|||
27423 | BPS Bioscience | 500 mg | EUR 440 |
Description: Biotinylation reagent with 3 PEG spacer. Has a carboxyl group with a free -OH that can react with activated surfaces or can be converted to another reactive functionality. |
Biotin-PEG3-Azide |
|||
27431 | BPS Bioscience | 100 mg | EUR 245 |
Description: Biotinylation reagent with Azide, and a 3 PEG spacer. Labels terminal alkynes via a copper-catalyzed "click reaction". Useful for labeling fluorescent dyes with triple bond alkyne groups. |
Biotin-PEG3-Azide |
|||
27432 | BPS Bioscience | 250 mg | EUR 395 |
Description: Biotinylation reagent with Azide, and a 3 PEG spacer. Labels terminal alkynes via a copper-catalyzed "click reaction". Useful for labeling fluorescent dyes with triple bond alkyne groups. |
Biotin-PEG3-Azide |
|||
27433 | BPS Bioscience | 500 mg | EUR 595 |
Description: Biotinylation reagent with Azide, and a 3 PEG spacer. Labels terminal alkynes via a copper-catalyzed "click reaction". Useful for labeling fluorescent dyes with triple bond alkyne groups. |
Biotin-PEG3-Hydrazide |
|||
27438 | BPS Bioscience | 100 mg | EUR 290 |
Description: Biotinylation reagent with Hydrazide, and a 3 PEG spacer. Reacts with aldehydes at pH 4 to 6. Can be used to label glycoproteins and other carbohydrate-containing compounds that have oxidizable sugars or aldehydes. Can also be used to biotinylate carboxyl groups. Popular label for antibodies, as the glycosylation sites are on the Fc region of the protein. |
Paternally Expressed 3 (PEG3) Antibody |
|||
20-abx013786 | Abbexa |
|
|
Paternally Expressed 3 (PEG3) Antibody |
|||
abx331093-100ul | Abbexa | 100 ul | EUR 510 |
Paternally Expressed 3 (PEG3) Antibody |
|||
20-abx323448 | Abbexa |
|
|
PEG3-tetrazine, 1 g |
|||
1978-1g | Lumiprobe | 1 g | EUR 793.2 |
PEG3-tetrazine, 250 mg |
|||
1978-250mg | Lumiprobe | 250 mg | EUR 366 |
Fmoc-nh-peg3-ch2cooh |
|||
20-abx180768 | Abbexa |
|
|
Boc-NH-PEG3-NH2 |
|||
20-abx180877 | Abbexa |
|
|
Bis-PEG3-NHS Ester |
|||
ADC-L-120 | Creative Biolabs | unit | Ask for price |
Human PEG3 shRNA Plasmid |
|||
20-abx953456 | Abbexa |
|
|
Mouse PEG3 shRNA Plasmid |
|||
20-abx971994 | Abbexa |
|
|
NH2-PEG3-C1-Boc |
|||
HY-128801 | MedChemExpress | 100mg | EUR 157.2 |
Biotin-PEG3-NHS ester |
|||
27440 | BPS Bioscience | 250 mg | EUR 310 |
Description: Biotinylation reagent with N-hydroxysuccinimide ester, and a 3 PEG spacer. The NHS group reacts with the e-amino group on lysines, the N-terminus of proteins, and other primary amines. |
Biotin-PEG3-NHS ester |
|||
27441 | BPS Bioscience | 500 mg | EUR 385 |
Description: Biotinylation reagent with N-hydroxysuccinimide ester, and a 3 PEG spacer. The NHS group reacts with the e-amino group on lysines, the N-terminus of proteins, and other primary amines. |
Alkyne-PEG3-OH, 1 g |
|||
418-1g | Lumiprobe | 1 g | EUR 111.6 |
Alkyne-PEG3-OH, 5 g |
|||
418-5g | Lumiprobe | 5 g | EUR 276 |
Azide-PEG3-Azide, 1 g |
|||
207-1g | Lumiprobe | 1 g | EUR 121.2 |
Azide-PEG3-Azide, 5 g |
|||
207-5g | Lumiprobe | 5 g | EUR 384 |
PEG3 dicarboxylic acid, 10 g |
|||
1715-10g | Lumiprobe | 10 g | EUR 1092 |
PEG3 dicarboxylic acid, 1 g |
|||
1715-1g | Lumiprobe | 1 g | EUR 423.6 |
PEG3 dicarboxylic acid, 5 g |
|||
1715-5g | Lumiprobe | 5 g | EUR 735.6 |
Alkyne-PEG3-COOH, 1 g |
|||
1743-1g | Lumiprobe | 1 g | EUR 418.8 |
Alkyne-PEG3-COOH, 5 g |
|||
1743-5g | Lumiprobe | 5 g | EUR 793.2 |
Azide-PEG3-Amine, 1 g |
|||
218-1g | Lumiprobe | 1 g | EUR 111.6 |
Azide-PEG3-Amine, 5 g |
|||
218-5g | Lumiprobe | 5 g | EUR 276 |
Biotin PEG3 azide, 25 mg |
|||
D3730 | Lumiprobe | 25 mg | EUR 116.4 |
Biotin PEG3 azide, 10 mg |
|||
C3730 | Lumiprobe | 10 mg | EUR 72 |
PEG3 ORF Vector (Human) (pORF) |
|||
ORF027601 | ABM | 1.0 ug DNA | EUR 790.8 |
Peg3 ORF Vector (Mouse) (pORF) |
|||
ORF053769 | ABM | 1.0 ug DNA | EUR 1886.4 |
Biotin PEG3 azide, 50 mg |
|||
E3730 | Lumiprobe | 50 mg | EUR 156 |
NH2-PEG3-C2-NH-Boc |
|||
HY-42776 | MedChemExpress | 100mg | EUR 129.6 |
N3-PEG3-vc-PAB-MMAE |
|||
HY-100874 | MedChemExpress | 5mg | EUR 1465.2 |
N3-PEG3-C2-NHS ester |
|||
HY-126528 | MedChemExpress | 500mg | EUR 3916.8 |
Pomalidomide-PEG3-C2-NH2 (TFA) |
|||
HY-128716A | MedChemExpress | 2g | EUR 6810 |
NHPI-PEG3-C2-Pfp ester |
|||
HY-130092 | MedChemExpress | 100mg | EUR 1011.6 |
NHPI-PEG3-C2-NHS ester |
|||
HY-130093 | MedChemExpress | 100mg | EUR 1011.6 |
Biotin PEG3 azide, 100 mg |
|||
F3730 | Lumiprobe | 100 mg | EUR 187.2 |
Biotin-PEG3-Amine-250 mg |
|||
78424-1 | BPS Bioscience | 250 mg | EUR 260 |
Description: Biotin-PEG3-amine is reactive with NHS ester or carboxylic acid in the presence of EDC or HATU. PEG3 increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. |
Biotin-PEG3-Amine-500 mg |
|||
78424-2 | BPS Bioscience | 500 mg | EUR 430 |
Description: Biotin-PEG3-amine is reactive with NHS ester or carboxylic acid in the presence of EDC or HATU. PEG3 increases aqueous solubility of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules. |
Biotin-PEG3-(CH2)3-Amine |
|||
27410 | BPS Bioscience | 100 mg | EUR 300 |
Description: Biotinylation reagent that binds the C-terminus of peptides and carboxylic acid groups on aspartate or glutamate residues. Contains a 3 PEG spacer arm. Requires the use of a crosslinker (e.g. EDC or DCC). |
Biotin-PEG3-(CH2)3-Amine |
|||
27411 | BPS Bioscience | 500 mg | EUR 565 |
Description: Biotinylation reagent that binds the C-terminus of peptides and carboxylic acid groups on aspartate or glutamate residues. Contains a 3 PEG spacer arm. Requires the use of a crosslinker (e.g. EDC or DCC). |
TMP-PEG3-amine, trifluoroacetic acid salt |
|||
91056 | Biotium | 1MG | EUR 234 |
Description: Minimum order quantity: 1 unit of 1MG |
PEG3-AS1 ORF Vector (Human) (pORF) |
|||
ORF027602 | ABM | 1.0 ug DNA | Ask for price |
PEG3 sgRNA CRISPR Lentivector set (Human) |
|||
K1626501 | ABM | 3 x 1.0 ug | EUR 406.8 |
(S,R,S)-AHPC-PEG3-N3 |
|||
HY-103598 | MedChemExpress | 2g | EUR 6810 |
(S,R,S)-AHPC-PEG3-NH2 |
|||
HY-103602A | MedChemExpress | 1g | EUR 4675.2 |
Thalidomide-O-amido-PEG3-C2-NH2 |
|||
HY-107440 | MedChemExpress | 2g | EUR 6810 |
Ald-Ph-amido-PEG3-C-COOH |
|||
HY-130098 | MedChemExpress | 100mg | EUR 693.6 |
Ald-Ph-amido-PEG3-C1-Boc |
|||
HY-130100 | MedChemExpress | 100mg | EUR 1011.6 |
Peg3 sgRNA CRISPR Lentivector set (Mouse) |
|||
K4341801 | ABM | 3 x 1.0 ug | EUR 406.8 |
PEG3 sgRNA CRISPR Lentivector (Human) (Target 1) |
|||
K1626502 | ABM | 1.0 ug DNA | EUR 184.8 |
PEG3 sgRNA CRISPR Lentivector (Human) (Target 2) |
|||
K1626503 | ABM | 1.0 ug DNA | EUR 184.8 |
PEG3 sgRNA CRISPR Lentivector (Human) (Target 3) |
|||
K1626504 | ABM | 1.0 ug DNA | EUR 184.8 |
(S,R,S)-AHPC-PEG3-NH2 (hydrochloride) |
|||
HY-103602 | MedChemExpress | 25mg | EUR 280.8 |
Thalidomide-O-amido-PEG3-C2-NH2 (TFA) |
|||
HY-103611 | MedChemExpress | 2g | EUR 6810 |
Ald-Ph-amido-PEG3-C2-Pfp ester |
|||
HY-130102 | MedChemExpress | 100mg | EUR 1011.6 |
Peg3 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
|||
K4341802 | ABM | 1.0 ug DNA | EUR 184.8 |
Peg3 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
|||
K4341803 | ABM | 1.0 ug DNA | EUR 184.8 |
Peg3 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
|||
K4341804 | ABM | 1.0 ug DNA | EUR 184.8 |
PEG3 Protein Vector (Human) (pPB-C-His) |
|||
PV110402 | ABM | 500 ng | EUR 2736 |
PEG3 Protein Vector (Human) (pPB-N-His) |
|||
PV110403 | ABM | 500 ng | EUR 2736 |
PEG3 Protein Vector (Human) (pPM-C-HA) |
|||
PV110404 | ABM | 500 ng | EUR 2736 |
PEG3 Protein Vector (Human) (pPM-C-His) |
|||
PV110405 | ABM | 500 ng | EUR 2736 |
PEG3 Protein Vector (Mouse) (pPB-C-His) |
|||
PV215074 | ABM | 500 ng | EUR 3175.2 |
PEG3 Protein Vector (Mouse) (pPB-N-His) |
|||
PV215075 | ABM | 500 ng | EUR 3175.2 |
PEG3 Protein Vector (Mouse) (pPM-C-HA) |
|||
PV215076 | ABM | 500 ng | EUR 3175.2 |
PEG3 Protein Vector (Mouse) (pPM-C-His) |
|||
PV215077 | ABM | 500 ng | EUR 3175.2 |
PEG3 3'UTR Luciferase Stable Cell Line |
|||
TU017722 | ABM | 1.0 ml | EUR 2799.6 |
PEG3 3'UTR GFP Stable Cell Line |
|||
TU067722 | ABM | 1.0 ml | EUR 2799.6 |
Peg3 3'UTR GFP Stable Cell Line |
|||
TU166185 | ABM | 1.0 ml | Ask for price |
Peg3 3'UTR Luciferase Stable Cell Line |
|||
TU116185 | ABM | 1.0 ml | Ask for price |
Anti-ERBB2 (trastuzumab)-Amino-PEG3-Propionyl-MMAE ADC |
|||
ADC-W-629 | Creative Biolabs | 1mg | Ask for price |
Description: This ADC product is comprised of an engineerd anti-ERBB2 antibody (trastuzumab with LLQGG tag at Fc) conjugated via a Amino-PEG3-Propionyl linker to MMAE |
(S,R,S)-AHPC-C6-PEG3-C4-Cl |
|||
HY-103605 | MedChemExpress | 1g | EUR 4675.2 |
Bovine Paternally- expressed gene 3 protein, PEG3 ELISA KIT |
|||
ELI-45910b | Lifescience Market | 96 Tests | EUR 1113.6 |
Mouse Paternally- expressed gene 3 protein, Peg3 ELISA KIT |
|||
ELI-20913m | Lifescience Market | 96 Tests | EUR 1038 |
Human Paternally- expressed gene 3 protein, PEG3 ELISA KIT |
|||
ELI-22084h | Lifescience Market | 96 Tests | EUR 988.8 |
PEG3-AS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV) |
|||
LV772727 | ABM | 1.0 ug DNA | Ask for price |
PEG3-AS1 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) |
|||
LV772731 | ABM | 1.0 ug DNA | Ask for price |
PEG3-AS1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) |
|||
LV772732 | ABM | 1.0 ug DNA | Ask for price |
PEG3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
|||
K1626505 | ABM | 3 x 1.0 ug | EUR 451.2 |
Peg3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
|||
K4341805 | ABM | 3 x 1.0 ug | EUR 451.2 |
PEG3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
|||
K1626506 | ABM | 1.0 ug DNA | EUR 200.4 |
PEG3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
|||
K1626507 | ABM | 1.0 ug DNA | EUR 200.4 |
PEG3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
|||
K1626508 | ABM | 1.0 ug DNA | EUR 200.4 |
Peg3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
|||
K4341806 | ABM | 1.0 ug DNA | EUR 200.4 |
Peg3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
|||
K4341807 | ABM | 1.0 ug DNA | EUR 200.4 |
Peg3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
|||
K4341808 | ABM | 1.0 ug DNA | EUR 200.4 |
PEG3-AS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) |
|||
LV772729 | ABM | 1.0 ug DNA | Ask for price |
PEG3-AS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) |
|||
LV772730 | ABM | 1.0 ug DNA | Ask for price |
CD11b Antibody Antibody |
|||
ABD2911 | Lifescience Market | 100 ug | EUR 525.6 |
ASAP1 antibody Antibody |
|||
DF8746 | Affbiotech | 200ul | EUR 420 |
anti- Antibody^Polyclonal antibody control antibody |
|||
LSMab09882 | Lifescience Market | 100 ug | EUR 525.6 |
ARHGDIA Antibody / RHOGDI Antibody |
|||
F54788-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
ARHGDIA Antibody / RHOGDI Antibody |
|||
F54788-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
Antibody |
|||
A1360-500 | Biovision | each | Ask for price |
Anti-Glycolipid Antibody (AGA) Antibody |
|||
20-abx004855 | Abbexa |
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
|||
20-abx008109 | Abbexa |
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
|||
20-abx123734 | Abbexa |
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
|||
20-abx014333 | Abbexa |
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
|||
abx033330-400ul | Abbexa | 400 ul | EUR 627.6 |
Ly1 Antibody Reactive (LYAR) Antibody |
|||
abx033330-80l | Abbexa | 80 µl | EUR 343.2 |
Anti-Glycolipid Antibody (AGA) Antibody |
|||
abx036399-100ug | Abbexa | 100 ug | EUR 469.2 |
Anti-Glycoprotein Antibody (GP) Antibody |
|||
20-abx319900 | Abbexa |
|
|
Anti-Glycoprotein Antibody (GP) Antibody |
|||
20-abx319901 | Abbexa |
|
|
Anti-Glycoprotein Antibody (GP) Antibody |
|||
20-abx319905 | Abbexa |
|
|
Anti-Glycoprotein Antibody (GP) Antibody |
|||
20-abx319913 | Abbexa |
|
|
Anti-Glycolipid Antibody (AGA) Antibody |
|||
abx230204-100ug | Abbexa | 100 ug | EUR 577.2 |
Ly1 Antibody Reactive (LYAR) Antibody |
|||
20-abx324434 | Abbexa |
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
|||
20-abx311665 | Abbexa |
|
|
Ly1 Antibody Reactive (LYAR) Antibody |
|||
abx234901-100ug | Abbexa | 100 ug | EUR 661.2 |
Anti-Anti-SEPT6 antibody antibody |
|||
STJ11100949 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. |
Anti-Anti-SEPT9 Antibody antibody |
|||
STJ111369 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
Anti-Anti-SEPT11 Antibody antibody |
|||
STJ111530 | St John's Laboratory | 100 µl | EUR 332.4 |
Anti-Anti-SEPT4 Antibody antibody |
|||
STJ112276 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
Anti-Anti-MARCH9 Antibody antibody |
|||
STJ112609 | St John's Laboratory | 100 µl | EUR 332.4 |
Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro mannequin of irritation
COVID-19 has posed a major risk to international well being. Early knowledge has revealed that IL-6, a key regulatory cytokine, performs an essential position within the cytokine storm of COVID-19. A number of trials are due to this fact wanting on the results of Tocilizumab, an IL-6 receptor antibody that inhibits IL-6 exercise, on remedy of COVID-19, with promising findings.
As a part of a scientific trial wanting on the results of Tocilizumab remedy on kidney transplant recipients with subclinical rejection, we carried out single-cell RNA sequencing of evaluating stimulated PBMCs earlier than and after Tocilizumab remedy. We leveraged this knowledge to create an in vitro cytokine storm mannequin, to higher perceive the consequences of Tocilizumab within the presence of irritation. Tocilizumab-treated cells had lowered expression of inflammatory-mediated genes and biologic pathways, notably amongst monocytes. These outcomes help the speculation that Tocilizumab might hinder the cytokine storm of COVID-19, by way of an indication of biologic influence on the single-cell degree.
Useful Characterization of a Putative RNA Demethylase ALKBH6 in Arabidopsis Development and Abiotic Stress Responses
RNA methylation and demethylation, which is mediated by RNA methyltransferases (known as “writers”) and demethylases (known as “erasers”), respectively, are rising as a key regulatory course of in plant growth and stress responses. Though a number of research have proven that AlkB homolog (ALKBH) proteins are potential RNA demethylases, the operate of most ALKBHs is but to be decided.
The Arabidopsis thaliana genome accommodates 13 genes encoding ALKBH proteins, the capabilities of that are largely unknown. On this research, we characterised the operate of a possible eraser protein, ALKBH6 (At4g20350), throughout seed germination and seedling progress in Arabidopsis below abiotic stresses. The seeds of T-DNA insertion alkbh6 knockdown mutants germinated quicker than the wild-type seeds below chilly, salt, or abscisic acid (ABA) remedy situations however not below dehydration stress situations.
Though no variations in seedling and root progress had been noticed between the alkbh6 mutant and wild-type below regular situations, the alkbh6 mutant confirmed a a lot decrease survival fee than the wild-type below salt, drought, or warmth stress. Cotyledon greening of the alkbh6 mutants was a lot greater than that of the wild-type upon ABA utility. Furthermore, the transcript ranges of ABA signaling-related genes, together with ABI3 and ABI4, had been down-regulated within the alkbh6 mutant in comparison with wild-type vegetation. Importantly, the ALKBH6 protein had a capability to bind to each m6A-labeled and m5C-labeled RNAs. Collectively, these outcomes point out that the potential eraser ALKBH6 performs essential roles in seed germination, seedling progress, and survival of Arabidopsis below abiotic stresses.
GNAS antibody |
|||
70R-13520 | Fitzgerald | 100 ul | EUR 548.4 |
Description: Affinity purified Rabbit polyclonal GNAS antibody |
GNAS antibody |
|||
38452-100ul | SAB | 100ul | EUR 302.4 |
GNAS Antibody |
|||
32899-100ul | SAB | 100ul | EUR 302.4 |
GNAS Antibody |
|||
ABD7068 | Lifescience Market | 100 ug | EUR 525.6 |
GNAS Antibody |
|||
ABD7388 | Lifescience Market | 100 ug | EUR 525.6 |
GNAS Antibody |
|||
DF7068 | Affbiotech | 200ul | EUR 420 |
GNAS Antibody |
|||
DF7388 | Affbiotech | 200ul | EUR 420 |
GNAS Antibody |
|||
1-CSB-PA147947 | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
GNAS Antibody |
|||
1-CSB-PA307619LA01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500 |
GNAS Antibody |
|||
1-CSB-PA352389LA01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
GNAS Antibody |
|||
1-CSB-PA247539 | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
GNAS Antibody |
|||
1-CSB-PA009596GA01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
GNAS Antibody |
|||
R35181-100UG | NSJ Bioreagents | 100 ug | EUR 399 |
GNAS Antibody |
|||
F40026-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
GNAS complex locus (GNAS) polyclonal antibody |
|||
ABP-PAB-11314 | Allele Biotech | 100 ug | Ask for price |
GNAS Complex Locus (GNAS) Antibody (HRP) |
|||
20-abx337231 | Abbexa |
|
|
GNAS Complex Locus (GNAS) Antibody (FITC) |
|||
20-abx337232 | Abbexa |
|
|
GNAS Complex Locus (GNAS) Antibody (Biotin) |
|||
20-abx337233 | Abbexa |
|
|
GNAS Antibody (HRP) |
|||
20-abx306647 | Abbexa |
|
|
GNAS Antibody (FITC) |
|||
20-abx306648 | Abbexa |
|
|
GNAS Antibody (Biotin) |
|||
20-abx306649 | Abbexa |
|
|
NESP55,GNAS Antibody |
|||
abx235663-100ug | Abbexa | 100 ug | EUR 577.2 |
GNAS Conjugated Antibody |
|||
C32899 | SAB | 100ul | EUR 476.4 |
Anti-GNAS antibody |
|||
PAab03536 | Lifescience Market | 100 ug | EUR 426 |
anti- GNAS antibody |
|||
FNab03536 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against GNAS |
Anti-GNAS antibody |
|||
STJ27492 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. |
Anti-GNAS antibody |
|||
STJ72252 | St John's Laboratory | 100 µg | EUR 430.8 |
Anti-GNAS antibody |
|||
STJ23816 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. |
GNAS Polyclonal Antibody |
|||
A64422-020 | EpiGentek | 20 ul | EUR 117.7 |
GNAS Polyclonal Antibody |
|||
A64422-050 | EpiGentek | 50 ul | EUR 302.5 |
GNAS Polyclonal Antibody |
|||
A64422-100 | EpiGentek | 100 ul | EUR 423.5 |
GNAS Polyclonal Antibody |
|||
A68803-020 | EpiGentek | 20 ul | Ask for price |
GNAS Polyclonal Antibody |
|||
A68803-050 | EpiGentek | 50 ul | Ask for price |
GNAS Polyclonal Antibody |
|||
A68803-100 | EpiGentek | 100 ul | EUR 470.8 |
GNAS Polyclonal Antibody |
|||
A64422 | EpiGentek |
|
|
GNAS Polyclonal Antibody |
|||
A68803 | EpiGentek |
|
|
Gnas/ Rat Gnas ELISA Kit |
|||
ELI-47242r | Lifescience Market | 96 Tests | EUR 1063.2 |
Gnas/ Rat Gnas ELISA Kit |
|||
ELI-35065r | Lifescience Market | 96 Tests | EUR 1063.2 |
Gnas/ Rat Gnas ELISA Kit |
|||
ELI-27931r | Lifescience Market | 96 Tests | EUR 1063.2 |
Gnas/ Rat Gnas ELISA Kit |
|||
ELI-12714r | Lifescience Market | 96 Tests | EUR 1063.2 |
GNAS Peptide |
|||
42-594P | ProSci | 0.1 mg | EUR 405.6 |
Description: (IN) GNAS Peptide |
GNAS siRNA |
|||
20-abx900009 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx900030 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918154 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918155 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918156 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918157 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918158 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918159 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918160 | Abbexa |
|
|
GNAS siRNA |
|||
20-abx918161 | Abbexa |
|
|
pBluescriptR-GNAS |
|||
PVT17793 | Lifescience Market | 2 ug | EUR 277.2 |
Polyclonal GNAS Antibody (Center) |
|||
APR05815G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GNAS (Center). This antibody is tested and proven to work in the following applications: |
GNAS Antibody, HRP conjugated |
|||
1-CSB-PA307619LB01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
GNAS Antibody, FITC conjugated |
|||
1-CSB-PA307619LC01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
GNAS Antibody, Biotin conjugated |
|||
1-CSB-PA307619LD01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
GNAS Antibody, HRP conjugated |
|||
1-CSB-PA352389LB01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
GNAS Antibody, FITC conjugated |
|||
1-CSB-PA352389LC01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
GNAS Antibody, Biotin conjugated |
|||
1-CSB-PA352389LD01HU | Cusabio |
|
|
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
anti- NESP55,GNAS antibody |
|||
FNab05663 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against NESP55,GNAS |
Polyclonal GNAS Antibody (N-Term) |
|||
AMM04827G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GNAS (N-Term). This antibody is tested and proven to work in the following applications: |
Polyclonal GNAS Antibody (aa385-394) |
|||
APR02185G | Leading Biology | 0.05mg | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GNAS (aa385-394). This antibody is tested and proven to work in the following applications: |
Monoclonal GNAS Antibody, Clone: 7G6G5 |
|||
AMM03034G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A Monoclonal antibody against Human GNAS. The antibodies are raised in Mouse and are from clone 7G6G5. This antibody is applicable in WB and IHC, FC, ICC, E |
Monoclonal GNAS Antibody, Clone: 2A2B7 |
|||
AMM03035G | Leading Biology | 0.1ml | EUR 633.6 |
Description: A Monoclonal antibody against Human GNAS. The antibodies are raised in Mouse and are from clone 2A2B7. This antibody is applicable in WB and IHC, FC, ICC, E |
Polyclonal GNAS Antibody (C-term) |
|||
APR04328G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GNAS (C-term). This antibody is tested and proven to work in the following applications: |
Polyclonal GNAS Antibody (internal region) |
|||
APG00677G | Leading Biology | 0.1mg | EUR 580.8 |
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human GNAS (internal region). This antibody is tested and proven to work in the following applications: |
GNAS Polyclonal Antibody, HRP Conjugated |
|||
A64423-050 | EpiGentek | 50 ul | EUR 302.5 |
GNAS Polyclonal Antibody, HRP Conjugated |
|||
A64423-100 | EpiGentek | 100 ul | EUR 423.5 |
GNAS Polyclonal Antibody, FITC Conjugated |
|||
A64424-050 | EpiGentek | 50 ul | EUR 302.5 |
GNAS Polyclonal Antibody, FITC Conjugated |
|||
A64424-100 | EpiGentek | 100 ul | EUR 423.5 |
GNAS Polyclonal Antibody, Biotin Conjugated |
|||
A64425-050 | EpiGentek | 50 ul | EUR 302.5 |
GNAS Polyclonal Antibody, Biotin Conjugated |
|||
A64425-100 | EpiGentek | 100 ul | EUR 423.5 |
GNAS Polyclonal Antibody, HRP Conjugated |
|||
A68804-050 | EpiGentek | 50 ul | EUR 293.7 |
GNAS Polyclonal Antibody, HRP Conjugated |
|||
A68804-100 | EpiGentek | 100 ul | EUR 470.8 |
GNAS Polyclonal Antibody, FITC Conjugated |
|||
A68805-050 | EpiGentek | 50 ul | EUR 293.7 |
GNAS Polyclonal Antibody, FITC Conjugated |
|||
A68805-100 | EpiGentek | 100 ul | EUR 470.8 |
GNAS Polyclonal Antibody, Biotin Conjugated |
|||
A68806-050 | EpiGentek | 50 ul | EUR 293.7 |
GNAS Polyclonal Antibody, Biotin Conjugated |
|||
A68806-100 | EpiGentek | 100 ul | EUR 470.8 |
GNAS Polyclonal Antibody, HRP Conjugated |
|||
A64423 | EpiGentek |
|
|
GNAS Polyclonal Antibody, FITC Conjugated |
|||
A64424 | EpiGentek |
|
|
GNAS Polyclonal Antibody, Biotin Conjugated |
|||
A64425 | EpiGentek |
|
|
GNAS Polyclonal Antibody, HRP Conjugated |
|||
A68804 | EpiGentek |
|
|
GNAS Polyclonal Antibody, FITC Conjugated |
|||
A68805 | EpiGentek |
|
|
GNAS Polyclonal Antibody, Biotin Conjugated |
|||
A68806 | EpiGentek |
|
|
GNAS Blocking Peptide |
|||
33R-8471 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GNAS antibody, catalog no. 70R-1652 |
GNAS Blocking Peptide |
|||
33R-9925 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GNAS antibody, catalog no. 70R-5756 |
GNAS Blocking Peptide |
|||
33R-6814 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GNAS antibody, catalog no. 70R-1643 |
GNAS Blocking Peptide |
|||
33R-10097 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GNAS antibody, catalog no. 70R-1651 |
GNAS Rabbit pAb |
|||
A2732-100ul | Abclonal | 100 ul | EUR 369.6 |
GNAS Rabbit pAb |
|||
A2732-200ul | Abclonal | 200 ul | EUR 550.8 |
GNAS Rabbit pAb |
|||
A2732-20ul | Abclonal | 20 ul | EUR 219.6 |
GNAS Rabbit pAb |
|||
A2732-50ul | Abclonal | 50 ul | EUR 267.6 |
GNAS Rabbit pAb |
|||
A5546-100ul | Abclonal | 100 ul | EUR 369.6 |
GNAS Rabbit pAb |
|||
A5546-200ul | Abclonal | 200 ul | EUR 550.8 |
GNAS Rabbit pAb |
|||
A5546-20ul | Abclonal | 20 ul | EUR 219.6 |
GNAS Rabbit pAb |
|||
A5546-50ul | Abclonal | 50 ul | EUR 267.6 |
GNAS Blocking Peptide |
|||
DF7068-BP | Affbiotech | 1mg | EUR 234 |
GNAS Blocking Peptide |
|||
DF7388-BP | Affbiotech | 1mg | EUR 234 |
GNAS cloning plasmid |
|||
CSB-CL009596HU1-10ug | Cusabio | 10ug | EUR 279.6 |
Description: A cloning plasmid for the GNAS gene. |
GNAS cloning plasmid |
|||
CSB-CL009596HU2-10ug | Cusabio | 10ug | EUR 279.6 |
Description: A cloning plasmid for the GNAS gene. |
Recombinant human GNAS |
|||
P1012 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human GNAS |
pSV40- Gnas- m |
|||
PVT11671 | Lifescience Market | 2 ug | EUR 327.6 |
GNAS Antibody (G protein alpha S) |
|||
F40026-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
Human GNAS shRNA Plasmid |
|||
20-abx951847 | Abbexa |
|
|
Human GNAS shRNA Plasmid |
|||
20-abx951848 | Abbexa |
|
|
Human GNAS shRNA Plasmid |
|||
20-abx951849 | Abbexa |
|
|
Human GNAS shRNA Plasmid |
|||
20-abx951850 | Abbexa |
|
|
Rat GNAS shRNA Plasmid |
|||
20-abx984695 | Abbexa |
|
|
Rat GNAS shRNA Plasmid |
|||
20-abx984696 | Abbexa |
|
|
Mouse GNAS shRNA Plasmid |
|||
20-abx970580 | Abbexa |
|
|
Mouse GNAS shRNA Plasmid |
|||
20-abx970581 | Abbexa |
|
|
Mouse GNAS shRNA Plasmid |
|||
20-abx970582 | Abbexa |
|
|
Mouse GNAS shRNA Plasmid |
|||
20-abx970583 | Abbexa |
|
|
GNAS ELISA KIT|Human |
|||
EF009911 | Lifescience Market | 96 Tests | EUR 826.8 |
Canine GNAS ELISA KIT |
|||
ELI-27250d | Lifescience Market | 96 Tests | EUR 1113.6 |
Mouse Gnas ELISA KIT |
|||
ELI-48020m | Lifescience Market | 96 Tests | EUR 1038 |
Human GNAS ELISA KIT |
|||
ELI-48772h | Lifescience Market | 96 Tests | EUR 988.8 |
Bovine GNAS ELISA KIT |
|||
ELI-38027b | Lifescience Market | 96 Tests | EUR 1113.6 |
Human GNAS ELISA KIT |
|||
ELI-12712h | Lifescience Market | 96 Tests | EUR 988.8 |
Mouse Gnas ELISA KIT |
|||
ELI-12713m | Lifescience Market | 96 Tests | EUR 1038 |
GNAS ELISA Kit (Human) (OKCA01388) |
|||
OKCA01388 | Aviva Systems Biology | 96 Wells | EUR 1015.2 |
Description: Description of target: ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 0.078 ng/mL |
GNAS ELISA Kit (Human) (OKEH08012) |
|||
OKEH08012 | Aviva Systems Biology | 96 Wells | EUR 1075.2 |
Description: Description of target: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.128ng/mL |
Gnas ORF Vector (Rat) (pORF) |
|||
ORF067655 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Rat) (pORF) |
|||
ORF067656 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Rat) (pORF) |
|||
ORF067657 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Rat) (pORF) |
|||
ORF067658 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Rat) (pORF) |
|||
ORF067659 | ABM | 1.0 ug DNA | EUR 607.2 |
GNAS ELISA Kit (Human) (OKWB00174) |
|||
OKWB00174 | Aviva Systems Biology | 96 Wells | EUR 686.4 |
Description: Description of target: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.;Species reactivity: Human;Application: ;Assay info: Assay Type: Quantitative Sandwich ELISA;Sensitivity: 46.9 nmol/mL |
GNAS ORF Vector (Human) (pORF) |
|||
ORF004496 | ABM | 1.0 ug DNA | EUR 114 |
GNAS ORF Vector (Human) (pORF) |
|||
ORF004497 | ABM | 1.0 ug DNA | EUR 114 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046308 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046309 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046310 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046311 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046312 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046313 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046314 | ABM | 1.0 ug DNA | EUR 607.2 |
Gnas ORF Vector (Mouse) (pORF) |
|||
ORF046315 | ABM | 1.0 ug DNA | EUR 607.2 |
NESP55/GNAS ELISA KIT|Human |
|||
EF001179 | Lifescience Market | 96 Tests | EUR 826.8 |
GNAS ELISA Kit (Rat) (OKCA01910) |
|||
OKCA01910 | Aviva Systems Biology | 96 Wells | EUR 1015.2 |
Description: Description of target: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as Gnas isoforms.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 0.078 ng/mL |
GNAS-AS1 ORF Vector (Human) (pORF) |
|||
ORF020250 | ABM | 1.0 ug DNA | EUR 114 |
Mouse Protein ALEX, Gnas ELISA KIT |
|||
ELI-24352m | Lifescience Market | 96 Tests | EUR 1038 |
Human Protein ALEX, GNAS ELISA KIT |
|||
ELI-24547h | Lifescience Market | 96 Tests | EUR 988.8 |
Gnas sgRNA CRISPR Lentivector set (Rat) |
|||
K7535001 | ABM | 3 x 1.0 ug | EUR 406.8 |
GNAS sgRNA CRISPR Lentivector set (Human) |
|||
K0875301 | ABM | 3 x 1.0 ug | EUR 406.8 |
Gnas sgRNA CRISPR Lentivector set (Mouse) |
|||
K4363501 | ABM | 3 x 1.0 ug | EUR 406.8 |
pECMV-3脳FLAG-GNAS vector |
|||
PVT12057 | Lifescience Market | 2 ug | EUR 422.4 |
Human Neuroendocrine Secretory Protein (GNAS) ELISA Kit |
|||
abx387603-96tests | Abbexa | 96 tests | EUR 1093.2 |
Mouse Neuroendocrine Secretory Protein (GNAS) ELISA Kit |
|||
abx392277-96tests | Abbexa | 96 tests | EUR 1093.2 |
Rat Neuroendocrine Secretory Protein (GNAS) ELISA Kit |
|||
abx392284-96tests | Abbexa | 96 tests | EUR 1093.2 |
Gnas sgRNA CRISPR Lentivector (Rat) (Target 1) |
|||
K7535002 | ABM | 1.0 ug DNA | EUR 184.8 |
Gnas sgRNA CRISPR Lentivector (Rat) (Target 2) |
|||
K7535003 | ABM | 1.0 ug DNA | EUR 184.8 |
Gnas sgRNA CRISPR Lentivector (Rat) (Target 3) |
|||
K7535004 | ABM | 1.0 ug DNA | EUR 184.8 |
GNAS sgRNA CRISPR Lentivector (Human) (Target 1) |
|||
K0875302 | ABM | 1.0 ug DNA | EUR 184.8 |
GNAS sgRNA CRISPR Lentivector (Human) (Target 2) |
|||
K0875303 | ABM | 1.0 ug DNA | EUR 184.8 |
GNAS sgRNA CRISPR Lentivector (Human) (Target 3) |
|||
K0875304 | ABM | 1.0 ug DNA | EUR 184.8 |
Gnas sgRNA CRISPR Lentivector (Mouse) (Target 1) |
|||
K4363502 | ABM | 1.0 ug DNA | EUR 184.8 |
Gnas sgRNA CRISPR Lentivector (Mouse) (Target 2) |
|||
K4363503 | ABM | 1.0 ug DNA | EUR 184.8 |
Gnas sgRNA CRISPR Lentivector (Mouse) (Target 3) |
|||
K4363504 | ABM | 1.0 ug DNA | EUR 184.8 |